Searchable abstracts of presentations at key conferences on calcified tissues

ba0004oc16 | (1) | ICCBH2015

Medicarpin, a natural pterocarpan, enhances bone regeneration in cortical bone defect model by activation of notch and Wnt canonical signalling pathway

Dixit Manisha , Raghuvanshi Ashutosh , Goel Atul , Singh Divya

Bone regeneration and fracture healing processes are impaired in post menopausal osteoporosis which is induced by estrogen deficiency. Though agents like BMPs and PTH have been shown to promote bone regeneration but are associated with undesirable side effects. There is a need for new agents that enhance bone regeneration and repair.The aim of this study was to evaluate the bone regenerative capacity of medicarpin in the osteoporotic rat model. Cortical ...